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For this, we exposed in vitro 3D microtissues (a maturing iPSC-derived cardiac model and a mature hepatic model) to 0.1% DMSO and we collected samples in triplicate at 7 different time points during 2 weeks exposure (2 h, 8 h, 24 h, 72 h, 168 h, 240 h and 336 h)

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Initially focused on metabolism, research showed NNMT elevation with age/weight leads to fat accumulation, inefficiency, and NAD+ loss.[30][31] High NNMT correlates with insulin resistance and obesity in humans